Pathology & Cancer Epidemiology

Breast cancer is the most common cancer and second leading cases of cancer related mortality.

 

Breast cancers can be divided into two main overarching groups: the carcinomas and the sarcomas. Carcinomas are cancers that arise from the epithelial component of the breast. The epithelial component consists of the cells that line the lobules and terminal ducts; under normal conditions, these epithelial cells are responsible for making milk. Carcinomas comprise the vast majority of all breast cancers and will be further discussed below. Sarcomas are rare cancers that arise from the stromal (connective tissue) components of the breast. These stromal component cells include myofibroblasts and blood vessel cells, and cancers arising from these "supportive" cells include phyllodes tumors and angiosarcoma. Sarcomas account for less than 1% of primary breast cancers.

 

Breast pathology is a rapidly developing discipline having crucial role in diagnosing breast diseases and in providing prognostic and predictive parameters that guide treatment decision.

 

Breast pathology plays a central role in the care of patients with diseases of the breast; an accurate, state-of-the-art diagnosis is the cornerstone of any further evaluation and management of the patient.

 

Breast cancers can be divided into two main overarching groups: the carcinomas and the sarcomas. Carcinomas are cancers that arise from the epithelial component of the breast. The epithelial component consists of the cells that line the lobules and terminal ducts; under normal conditions, these epithelial cells are responsible for making milk. Carcinomas comprise the vast majority of all breast cancers and will be further discussed below. Sarcomas are rare cancers that arise from the stromal (connective tissue) components of the breast. These stromal component cells include myofibroblasts and blood vessel cells, and cancers arising from these "supportive" cells include phyllodes tumors and angiosarcoma. Sarcomas account for less than 1% of primary breast cancers.

 

Bosom malignancy is the most well-known growth and second driving instances of disease related mortality.

 

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